AV¶ÌÊÓÆµ

Pei-Hsuan Wu

Publications

Selected publications

  • 2024     (Commentary) Haase AD, Ketting RF, Lai EC, van Rij RP, Siomi M, Svoboda P, van Wolfswinkel JC, Wu PH. PIWI-interacting RNAs: who, what, when, where, why, and how. EMBO Journal.

  • 2023     Gainetdinov I, Vega-Badillo J, Cecchini K, Bagci A, Colpan C, De D, Bailey S, Arif A, Wu PH, MacRae IJ, Zamore PD. Relaxed targeting rules help PIWI proteins silence transposons. Nature.
  • 2023     (Review) Perillo G*, Shibata K*, Wu PH. piRNAs in sperm function and embryo viability. Reproduction. *equal contribution.
  • 2022     Rosell AL, Paglione M, Gilley J, Kocia M, Perillo G, Gasparrini M, Cialabrini L, Raffaelli N, Angeletti C, Orsomando G, Wu PH, Coleman MP, Loreto A, Neukomm LJ. The NAD+ precursor NMN activates dSarm to trigger axon degeneration in Drosophila. eLife.
  • 2021     (Preview) Wu PH* and Zamore PD*. To degrade a microRNA, destroy its Argonaute protein. Molecular Cell. *co-corresponding authors.
  • 2021     (Review) Wu PH* and Zamore PD*. Defining the functions of PIWI-interacting RNAs. Nature Reviews Molecular Cell Biology. *co-corresponding authors.
  • 2020     Wu PH*, Fu Y, Cecchini K, Ozata DM, Arif A, Yu T, Colpan C, Gainetdinov I, Weng Z*, Zamore PD*. The evolutionarily conserved piRNA-producing locus pi6 is required for male mouse fertility. Nature Genetics. *co-corresponding authors.
  • 2020     Ozata DM, Yu T, Mou H, Gainetdinov I, Colpan C, Cecchini K, Kaymaz Y, Wu PH, Fan K, Kucukural A,  Weng Z, Zamore PD. (2020) Evolutionarily conserved pachytene piRNA loci are diverging rapidly among modern humans. Nature Ecology and Evolution.
  • 2018     (Methods) Fu Y*, Wu PH*, Beane T, Zamore PD, Weng Z. Elimination of PCR duplicates in RNA-seq and small RNA-seq using unique molecular identifiers. *equal contribution.
  • 2018     Wang D, Li J, Song CQ, Tran K, Mou H, Wu PH, Tai PWL, Mendonca CA, Ren L, Wang BY, Su Q, Gessler DJ, Zamore PD, Xue W, Gao G. Cas9-mediated allelic exchange repairs compound heterozygous recessive mutations in mice. Nature Biotechnology.


See all publications on .