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A review on calcium in skeletal muscle

Calcium is essential to the functioning of all cells and plays a particular role in skeletal muscle. One of the key mechanisms of calcium regulation, the store-operated calcium entry SOCE, has been extensively studied. However, knowledge about its functioning in skeletal muscle remains sparse.

, researchers from the group of Prof. Maud Frieden, together with the group of Dr. Xaver Koenig in Vienna, discuss what differentiates skeletal muscle SOCE from its counterpart found in non-excitable cells. They highlight the complexity of SOCE activation and its regulation in skeletal muscle, with the aim to reach a better picture of this mesmerizing phenomenon.

 

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Microscopy image of skeletal muscle © UNIGE

 

 

 

 

 

 

 

11 Oct 2021

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