AV短视频

We are interested in integrating unorthodox, at best new interactions into catalysis. This is important because new ways to interact should lead to new reactivity. In this spirit, we have introduced catalysis with anion-蟺 interactions in 2013, followed by catalysis with chalcogen bonds in 2017 and catalysis with pnictogen bonds in 2018. In 2023, we realized electric-field catalysis on carbon nanotubes in electromicrofluidic reactors, combined with anion-蟺 and cation-蟺 catalysis, depending on the orientation of the field. Theory and biology predict that concept to accelerate and direct electron movement during reactions with oriented external electric fields (OEEFs) could change the way we make molecules, but practical challenges under scalable bulk conditions have so far hindered general use in academia and industry.

Methods: These projects generate expertise in synthetic methodology, in combination with total synthesis, electromicrofluidics methods development, carbon allotropes (mostly nanotubes, surface chemistry, non/covalent modifications, self-assembly), kinetics (NMR, HPLC, GC), analysis (chemo-/enantioselectivity, rate enhancements, proficiency, ground-state vs transition-state stabilization) and (optional) extension to molecular modeling, materials characterization, and biocatalysis.

Collaborations: These projects offer optional in-house collaboration possibilities with regard to computational chemistry and ultrafast photophysics. They are connected to the , with possible collaboration with other members (artificial enzymes, device engineering), NCCR group meetings and retreats.

Recommended reading:

Guti茅rrez L贸pez, M. 脕.; Ali, R.; Tan, M.-L.; Sakai, N.; Wirth, T.; Matile, S. 鈥淓lectric Field-Assisted Anion-蟺 Catalysis on Carbon Nanotubes in Electrochemical Microfluidic Devices,鈥�

Zhao, Y.; Cotelle, Y.; Liu, L.; Lopez-Andarias, J.; Bornhof, A.-B.; Akamatsu, M.; Sakai, N.; Matile, S. 鈥淭he Emergence of Anion-蟺 Catalysis,鈥�

Renno, G.; Chen, D.; Zhang, Q.-X.; Gomila, R. M.; Frontera, A.; Sakai, N.; Ward, T. R.; Matile, S. 鈥淧nictogen-Bonding Enzymes,鈥�

Benz, S.; Poblador-Bahamonde, A. I.; Low-Ders, N.; Matile, S. 鈥淐atalysis with Pnictogen, Chalcogen and Halogen Bonds,鈥�

Benz, S.; Lopez-Andarias, J.; Mareda, J.; Sakai, N.; Matile, S. 鈥淐atalysis with Chalcogen Bonds,鈥�

Zhao, Y.; Domoto, Y.; Orentas, E.; Beuchat, C.; Emery, D.; Mareda, J.; Sakai, N.; Matile, S. 鈥淐atalysis with Anion-蟺 Interactions,鈥�