Welcome to the F眉rstenberg group website
Our general research interests lie in the development and application of optical spectroscopic and microscopic tools to address quantitatively chemical and biological questions at the molecular scale, with an emphasis on single-molecule techniques using smart fluorescence sensors to study biomolecular structure and dynamics. We are interested in understanding and controlling the photophysics of fluorescent probes in order to use them as quantitative local probes of their direct environment. Our routine portfolio of techniques encompasses single-molecule fluorescence spectroscopy and imaging, super-resolution imaging, fluorescence correlation spectroscopy, and fluorescence lifetime measurements in the bulk or at the single-molecule level.
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LATEST PUBLICATIONS
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Enhancing the Brightness of Red-emitting Fluorophores in Aqueous Solution by Molecular Encapsulation
Liza Briant and Alexandre F眉rstenberg
Chimia 2025, 79(4), 259-262
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Super-Resolution Imaging with a Cucurbituril-Encapsulated Fluorophore
Liza Briant, Jimmy Maillard, and Alexandre F眉rstenberg
Chem. Commun. 2024, 60(94), 13943-13946
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Single-Molecule Localization Microscopy and Tracking with a Fluorescent Mechanosensitive Probe
Jimmy Maillard, Ewa Grassin, Ekaterina Bestsennaia, Melinda Silaghi, Karolina Strakov谩, Jos茅 Garc铆a-Calvo, Naomi Sakai, Stefan Matile, and Alexandre F眉rstenberg
J. Phys. Chem. B 2024, 128(33), 7997-8006
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Local Water Content in Polymer Gels Measured With Super-Resolved Fluorescence Lifetime Imaging
Sankar Jana, Oleksii Nevskyi, Hannah H枚che, Leon Trottenberg, Eric Siemes, J枚rg Enderlein, Alexandre F眉rstenberg, and Dominik W枚ll
Angew. Chem. Int. Ed. 2024, 63(10), e202318421
WHAT'S NEW?
March 6, 2025: The installation of our new microscope is now finished. We are looking forward to performing some cool experiments with it!!
March 3, 2025: Gladys Jaccard joined the group for her extra muros master thesis. Welcome back to Geneva Gladys!
September 5, 2024: Congratulations to Liza who won the award for the best talk in physical chemistry at the Swiss Chemical Society Fall Meeting in Fribourg!!
October 2, 2023: Nicolas Borgnana joined the group as a PhD student. Welcome back to the lab Nicolas!
February 6, 2023: Congratulations to Dr. Jimmy Maillard who successfully defended his PhD!
January 6, 2023: Ekaterina Bestsennaia joined the group as a PhD student. Welcome to Geneva Katia!
December 8, 2022: Congratulations to Dr. Levente Juhasz who successfully defended his PhD!