Publications
2023
- Simon, Clémence; Asaro, Antonino; Feng, Suihan; Riezman, Howard (2023) An organelle-specific photoactivation and dual-isotope labeling strategy reveals phosphatidylethanolamine metabolic flux. .
- Umebayashi, Miwa; Takemoto, Satoko; Reymond, Luc; Sundukova, Mayya; Hovius, Ruud; Bucci, Annalisa; Heppenstall, Paul A.; Yokota, Hideo; Johnsson, Kai; Riezman, Howard (2023) A covalently linked probe to monitor local membrane properties surrounding plasma membrane proteins. .
2022
- Petrenko, Volodymyr; Sinturel, Flore; Loizides-Mangold, Ursula; Montoya, Jonathan Paz; Chera, Simona; Riezman, Howard; Dibner, Charna; Hattar, Samer (2022) Type 2 diabetes disrupts circadian orchestration of lipid metabolism and membrane fluidity in human pancreatic islets. .
- Girik, Vladimir; Feng, Suihan; Hariri, Hanaa; Henne, W. Mike; Riezman, Howard (2022) Vacuole-Specific Lipid Release for Tracking Intracellular Lipid Metabolism and Transport in Saccharomyces cerevisiae. .
- Merino, Marisa M.; Seum, Carole; Dubois, Marine; Gonzalez-Gaitan, Marcos (2022) A role for Flower and cell death in controlling morphogen gradient scaling. .
- Monasterio, Bingen G.; Jiménez-Rojo, Noemi; García-Arribas, Aritz B.; Riezman, Howard; Goñi, Félix M.; Alonso, Alicia (2022) Plasma membrane effects of sphingolipid-synthesis inhibition by myriocin in CHO cells: a biophysical and lipidomic study. .
2021
- Assies, Lea; García-Calvo, José; Piazzolla, Francesca; Sanchez, Samantha; Kato, Takehiro; Reymond, Luc; Goujon, Antoine; Colom, Adai; López-Andarias, Javier; Straková, Karolína; Mahecic, Dora; Mercier, Vincent; Riggi, Margot; Jiménez-Rojo, Noemi; Roffay, Chloé; Licari, Giuseppe; Tsemperouli, Maria; Neuhaus, Frederik; Fürstenberg, Alexandre; Vauthey, Eric; Hoogendoorn, Sascha; Gonzalez-Gaitan, Marcos; Zumbuehl, Andreas; Sugihara, Kaori; Gruenberg, Jean; Riezman, Howard; Loewith, Robbie; Manley, Suliana; Roux, Aurelien; Winssinger, Nicolas; Sakai, Naomi; Pitsch, Stefan; Matile, Stefan (2021) Flipper Probes for the Community. .
- Aguilera-Romero, Auxiliadora; Sabido-Bozo, Susana; Lopez, Sergio; Cortes-Gomez, Alejandro; Rodriguez-Gallardo, Sofia; Perez-Linero, Ana Maria; Riezman, Isabelle; Riezman, Howard; Muñiz, Manuel; Polymenis, Michael (2021) Determination of the lipid composition of the GPI anchor. .
- Cadena del Castillo, Carla E.; Hannich, J. Thomas; Kaech, Andres; Chiyoda, Hirohisa; Brewer, Jonathan; Fukuyama, Masamitsu; Færgeman, Nils J.; Riezman, Howard; Spang, Anne (2021) Patched regulates lipid homeostasis by controlling cellular cholesterol levels. .
- Monasterio, Bingen G.; Jiménez-Rojo, Noemi; García-Arribas, Aritz B.; Riezman, Howard; Goñi, Félix M.; Alonso, Alicia (2021) CHO/LY-B cell growth under limiting sphingolipid supply: Correlation between lipid composition and biophysical properties of sphingolipid-restricted cell membranes. .
- Chang, Dalu; Feng, Suihan; Girik, Vladimir; Riezman, Howard; Winssinger, Nicolas (2021) Luciferase Controlled Protein Interactions. .
- Morstein, Johannes; Kol, Matthijs; Novak, Alexander J. E.; Feng, Suihan; Khayyo, Shadi; Hinnah, Konstantin; Li-Purcell, Nasi; Pan, Grace; Williams, Benjamin M.; Riezman, Howard; Atilla-Gokcumen, G. Ekin; Holthuis, Joost C. M.; Trauner, Dirk (2021) Short Photoswitchable Ceramides Enable Optical Control of Apoptosis. .
- López-Andarias, Javier; Straková, Karolína; Martinent, Rémi; Jiménez-Rojo, Noemi; Riezman, Howard; Sakai, Naomi; Matile, Stefan (2021) Genetically Encoded Supramolecular Targeting of Fluorescent Membrane Tension Probes within Live Cells: Precisely Localized Controlled Release by External Chemical Stimulation. .
- Hannich, J. Thomas; Loizides-Mangold, Ursula; Sinturel, Flore; Harayama, Takeshi; Vandereycken, Bart; Saini, Camille; Gosselin, Pauline; Brulhart-Meynet, Marie-Claude; Robert, Maud; Chanon, Stephanie; Durand, Christine; Paz Montoya, Jonathan; David, Fabrice P. A.; Guessous, Idris; Pataky, Zoltan; Golay, Alain; Jornayvaz, François R.; Philippe, Jacques; Dermitzakis, Emmanouil T.; Brown, Steven A.; Lefai, Etienne; Riezman, Howard; Dibner, Charna (2021) Ether lipids, sphingolipids and toxic 1-deoxyceramides as hallmarks for lean and obese type 2 diabetic patients. .
2020
- Rodriguez-Gallardo, Sofia; Kurokawa, Kazuo; Sabido-Bozo, Susana; Cortes-Gomez, Alejandro; Ikeda, Atsuko; Zoni, Valeria; Aguilera-Romero, Auxiliadora; Perez-Linero, Ana Maria; Lopez, Sergio; Waga, Miho; Araki, Misako; Nakano, Miyako; Riezman, Howard; Funato, Kouichi; Vanni, Stefano; Nakano, Akihiko; Muñiz, Manuel (2020) Ceramide chain length–dependent protein sorting into selective endoplasmic reticulum exit sites. .
- Ikeda, Atsuko; Schlarmann, Philipp; Kurokawa, Kazuo; Nakano, Akihiko; Riezman, Howard; Funato, Kouichi (2020) Tricalbins Are Required for Non-vesicular Ceramide Transport at ER-Golgi Contacts and Modulate Lipid Droplet Biogenesis. .
- Jiménez-Rojo, Noemi; Leonetti, Manuel D.; Zoni, Valeria; Colom, Adai; Feng, Suihan; Iyengar, Namrata R.; Matile, Stefan; Roux, Aurélien; Vanni, Stefano; Weissman, Jonathan S.; Riezman, Howard (2020) Conserved Functions of Ether Lipids and Sphingolipids in the Early Secretory Pathway. .
- Straková, Karolína; López-Andarias, Javier; Jiménez-Rojo, Noemi; Chambers, Joseph E.; Marciniak, Stefan J.; Riezman, Howard; Sakai, Naomi; Matile, Stefan (2020) HaloFlippers: A General Tool for the Fluorescence Imaging of Precisely Localized Membrane Tension Changes in Living Cells. .
- Hoch, Dominic G.; Abegg, Daniel; Hannich, J. Thomas; Pechalrieu, Dany; Shuster, Anton; Dwyer, Brendan G.; Wang, Chao; Zhang, Xiaojin; You, Qidong; Riezman, Howard; Adibekian, Alexander (2020) Combined Omics Approach Identifies Gambogic Acid and Related Xanthones as Covalent Inhibitors of the Serine Palmitoyltransferase Complex. .
- Funato, Kouichi; Riezman, Howard; Muñiz, Manuel (2020) Vesicular and non-vesicular lipid export from the ER to the secretory pathway. .
2019
- Líndez, Adrià-Arnau Martí; Dunand-Sauthier, Isabelle; Conti, Mark; Gobet, Florian; Núñez, Nicolás; Hannich, J. Thomas; Riezman, Howard; Geiger, Roger; Piersigilli, Alessandra; Hahn, Kerstin; Lemeille, Sylvain; Becher, Burkhard; De Smedt, Thibaut; Hugues, Stéphanie; Reith, Walter (2019) Mitochondrial arginase-2 is a cell?autonomous regulator of CD8+ T cell function and antitumor efficacy. .
- Haribowo, A. Galih; Hannich, J. Thomas; Michel, Agnès H.; Megyeri, Márton; Schuldiner, Maya; Kornmann, Benoît; Riezman, Howard; Parton, Robert G. (2019) Cytotoxicity of 1-deoxysphingolipid unraveled by genome-wide genetic screens and lipidomics in Saccharomyces cerevisiae. .
- Chang, Dalu; Lindberg, Eric; Feng, Suihan; Angerani, Simona; Riezman, Howard; Winssinger, Nicolas (2019) Luciferase-Induced Photouncaging: Bioluminolysis. .
- Jiménez-Rojo, Noemi; Riezman, Howard (2019) On the road to unraveling the molecular functions of ether lipids. .
- Megyeri, Márton; Prasad, Rupali; Volpert, Giora; Sliwa-Gonzalez, Andrzej; Galih, Augustinus; Aguilera-Romero, Auxiliadora; Riezman, Howard; Barral, Yves; Futerman, Anthony H.; Schuldiner, Maya (2019) Yeast ceramide synthases, Lag1 and Lac1, have distinct substrate specificity. .
- Morstein, Johannes; Hill, Rose Z.; Novak, Alexander J. E.; Feng, Suihan; Norman, Derek D.; Donthamsetti, Prashant C.; Frank, James A.; Harayama, Takeshi; Williams, Benjamin M.; Parrill, Abby L.; Tigyi, Gabor J.; Riezman, Howard; Isacoff, Ehud Y.; Bautista, Diana M.; Trauner, Dirk (2019) Optical control of sphingosine-1-phosphate formation and function. .
- Loewith, Robbie; Riezman, Howard; Winssinger, Nicolas (2019) Sphingolipids and membrane targets for therapeutics. .
- Feng, Suihan; Harayama, Takeshi; Chang, Dalu; Hannich, J. Thomas; Winssinger, Nicolas; Riezman, Howard (2019) Lysosome-targeted photoactivation reveals local sphingosine metabolism signatures. .
- Sundukova, Mayya; Prifti, Efthymia; Bucci, Annalisa; Kirillova, Kseniia; Serrao, Joana; Reymond, Luc; Umebayashi, Miwa; Hovius, Ruud; Riezman, Howard; Johnsson, Kai; Heppenstall, Paul A. (2019) A Chemogenetic Approach for the Optical Monitoring of Voltage in Neurons. .
2018
- He, Cuiwen; Hu, Xuchen; Weston, Thomas A.; Jung, Rachel S.; Sandhu, Jaspreet; Huang, Song; Heizer, Patrick; Kim, Jason; Ellison, Rochelle; Xu, Jiake; Kilburn, Matthew; Bensinger, Steven J.; Riezman, Howard; Tontonoz, Peter; Fong, Loren G.; Jiang, Haibo; Young, Stephen G. (2018) Macrophages release plasma membrane-derived particles rich in accessible cholesterol. .
- Melero, Alejandro; Chiaruttini, Nicolas; Karashima, Takefumi; Riezman, Isabelle; Funato, Kouichi; Barlowe, Charles; Riezman, Howard; Roux, Aurélien (2018) Lysophospholipids Facilitate COPII Vesicle Formation. .
- Perrin, Laurent; Loizides-Mangold, Ursula; Chanon, Stéphanie; Gobet, Cédric; Hulo, Nicolas; Isenegger, Laura; Weger, Benjamin D.; Migliavacca, Eugenia; Charpagne, Aline; Betts, James A.; Walhin, Jean-Philippe; Templeman, Iain; Stokes, Keith; Thompson, Dylan; Tsintzas, Kostas; Robert, Maud; Howald, Cedric; Riezman, Howard; Feige, Jerome N.; Karagounis, Leonidas G.; Johnston, Jonathan D.; Dermitzakis, Emmanouil T.; Gachon, Frédéric; Lefai, Etienne; Dibner, Charna (2018) Transcriptomic analyses reveal rhythmic and CLOCK-driven pathways in human skeletal muscle. .
- Harayama, Takeshi; Riezman, Howard (2018) Understanding the diversity of membrane lipid composition. .
- Feng, Suihan; Harayama, Takeshi; Montessuit, Sylvie; David, Fabrice P. A.; Winssinger, Nicolas; Martinou, Jean-Claude; Riezman, Howard (2018) Mitochondria-specific photoactivation to monitor local sphingosine metabolism and function. .
- Kawano, Shin; Tamura, Yasushi; Kojima, Rieko; Bala, Siqin; Asai, Eri; Michel, Agnès H.; Kornmann, Benoît; Riezman, Isabelle; Riezman, Howard; Sakae, Yoshitake; Okamoto, Yuko; Endo, Toshiya (2018) Structure–function insights into direct lipid transfer between membranes by Mmm1–Mdm12 of ERMES. .
- Shinde, Abhijit Babaji; Baboota, Ritesh Kumar; Denis, Simone; Loizides-Mangold, Ursula; Peeters, Annelies; Espeel, Marc; Malheiro, Ana Rita; Riezman, Howard; Vinckier, Stefan; Vaz, Frédéric M.; Brites, Pedro; Ferdinandusse, Sacha; Van Veldhoven, Paul P.; Baes, Myriam (2018) Mitochondrial disruption in peroxisome deficient cells is hepatocyte selective but is not mediated by common hepatic peroxisomal metabolites. .
2017
- Guri, Yakir; Colombi, Marco; Dazert, Eva; Hindupur, Sravanth K.; Roszik, Jason; Moes, Suzette; Jenoe, Paul; Heim, Markus H.; Riezman, Isabelle; Riezman, Howard; Hall, Michael N. (2017) mTORC2 Promotes Tumorigenesis via Lipid Synthesis. .
- Loizides-Mangold, Ursula; Perrin, Laurent; Vandereycken, Bart; Betts, James A.; Walhin, Jean-Philippe; Templeman, Iain; Chanon, Stéphanie; Weger, Benjamin D.; Durand, Christine; Robert, Maud; Paz Montoya, Jonathan; Moniatte, Marc; Karagounis, Leonidas G.; Johnston, Jonathan D.; Gachon, Frédéric; Lefai, Etienne; Riezman, Howard; Dibner, Charna (2017) Lipidomics reveals diurnal lipid oscillations in human skeletal muscle persisting in cellular myotubes cultured in vitro. .
- Dewhurst-Maridor, Gisèle; Abegg, Daniel; David, Fabrice P.A.; Rougemont, Jacques; Scott, Cameron C.; Adibekian, Alexander; Riezman, Howard; Drubin, David G. (2017) The SAGA complex, together with transcription factors and the endocytic protein Rvs167p, coordinate the reprofiling of gene expression in response to changes in sterol composition in Saccharomyces cerevisiae. .
- Guerreiro, Joana F.; Mira, Nuno P.; Santos, Aline X. S.; Riezman, Howard; Sá-Correia, Isabel (2017) Membrane Phosphoproteomics of Yeast Early Response to Acetic Acid: Role of Hrk1 Kinase and Lipid Biosynthetic Pathways, in Particular Sphingolipids. .
- Dorsaz, Stéphane; Snäka, Tiia; Favre-Godal, Quentin; Maudens, Pierre; Boulens, Nathalie; Furrer, Pascal; Ebrahimi, Samad Nejad; Hamburger, Matthias; Allémann, Eric; Gindro, Katia; Queiroz, Emerson Ferreira; Riezman, Howard; Wolfender, Jean-Luc; Sanglard, Dominique (2017) Identification and mode of action of a plant natural product targeting human fungal pathogens. .
- Harayama, Takeshi; Riezman, Howard (2017) Detection of genome-edited mutant clones by a simple competition-based PCR method. .
- Capasso, Serena; Sticco, Lucia; Rizzo, Riccardo; Pirozzi, Marinella; Russo, Domenico; Dathan, Nina A; Campelo, Felix; van Galen, Josse; Hölttä-Vuori, Maarit; Turacchio, Gabriele; Hausser, Angelika; Malhotra, Vivek; Riezman, Isabelle; Riezman, Howard; Ikonen, Elina; Luberto, Chiara; Parashuraman, Seetharaman; Luini, Alberto; D'Angelo, Giovanni (2017) Sphingolipid metabolic flow controls phosphoinositide turnover at the trans-Golgi network. .
- Hannich, J. Thomas; Mellal, Denia; Feng, Suihan; Zumbuehl, Andreas; Riezman, Howard (2017) Structure and conserved function of iso-branched sphingoid bases from the nematode Caenorhabditis elegans. .
- Zimmermann, Christine; Santos, Aline; Gable, Kenneth; Epstein, Sharon; Gururaj, Charulatha; Chymkowitch, Pierre; Pultz, Dennis; Rødkær, Steven V.; Clay, Lorena; Bjørås, Magnar; Barral, Yves; Chang, Amy; Færgeman, Nils J.; Dunn, Teresa M.; Riezman, Howard; Enserink, Jorrit M. (2017) Correction: TORC1 Inhibits GSK3-Mediated Elo2 Phosphorylation to Regulate Very Long Chain Fatty Acid Synthesis and Autophagy. .
- Lovric, Svjetlana; Goncalves, Sara; Gee, Heon Yung; Oskouian, Babak; Srinivas, Honnappa; Choi, Won-Il; Shril, Shirlee; Ashraf, Shazia; Tan, Weizhen; Rao, Jia; Airik, Merlin; Schapiro, David; Braun, Daniela A.; Sadowski, Carolin E.; Widmeier, Eugen; Jobst-Schwan, Tilman; Schmidt, Johanna Magdalena; Girik, Vladimir; Capitani, Guido; Suh, Jung H.; Lachaussée, Noëlle; Arrondel, Christelle; Patat, Julie; Gribouval, Olivier; Furlano, Monica; Boyer, Olivia; Schmitt, Alain; Vuiblet, Vincent; Hashmi, Seema; Wilcken, Rainer; Bernier, Francois P.; Innes, A. Micheil; Parboosingh, Jillian S.; Lamont, Ryan E.; Midgley, Julian P.; Wright, Nicola; Majewski, Jacek; Zenker, Martin; Schaefer, Franz; Kuss, Navina; Greil, Johann; Giese, Thomas; Schwarz, Klaus; Catheline, Vilain; Schanze, Denny; Franke, Ingolf; Sznajer, Yves; Truant, Anne S.; Adams, Brigitte; Désir, Julie; Biemann, Ronald; Pei, York; Ars, Elisabet; Lloberas, Nuria; Madrid, Alvaro; Dharnidharka, Vikas R.; Connolly, Anne M.; Willing, Marcia C.; Cooper, Megan A.; Lifton, Richard P.; Simons, Matias; Riezman, Howard; Antignac, Corinne; Saba, Julie D.; Hildebrandt, Friedhelm (2017) Mutations in sphingosine-1-phosphase lyase cause nephrosis with ichthyosis and adrenal insufficiency. .
2016
- Megyeri, Márton; Riezman, Howard; Schuldiner, Maya; Futerman, Anthony H. (2016) Making Sense of the Yeast Sphingolipid Pathway. .
- Sikorska, Natalia; Lemus, Leticia; Aguilera-Romero, Auxiliadora; Manzano-Lopez, Javier; Riezman, Howard; Muñiz, Manuel; Goder, Veit (2016) Limited ER quality control for GPI-anchored proteins. .
- Savoglidis, Georgios; da Silveira dos Santos, Aline Xavier; Riezman, Isabelle; Angelino, Paolo; Riezman, Howard; Hatzimanikatis, Vassily (2016) A method for analysis and design of metabolism using metabolomics data and kinetic models: application on lipidomics using a novel kinetic model of sphingolipid metabolism. .
- Muñiz, Manuel; Riezman, Howard (2016) Trafficking of glycosylphosphatidylinositol anchored proteins from the endoplasmic reticulum to the cell surface. .
2015
- Garcia, Alba Alfonso; Pfisterer, Simon G.; Riezman, Howard; Ikonen, Elina; Potma, Eric O. (2015) D38-cholesterol as a Raman active probe for imaging intracellular cholesterol storage. .
- Höglinger, Doris; Haberkant, Per; Aguilera-Romero, Auxiliadora; Riezman, Howard; Porter, Forbes D.; Platt, Frances M.; Galione, Antony; Schultz, Carsten (2015) Intracellular sphingosine releases calcium from lysosomes. .
- Blom, Tomas; Li, Shiqian; Dichlberger, Andrea; Bäck, Nils; Kim, Young Ah; Loizides-Mangold, Ursula; Riezman, Howard; Bittman, Robert; Ikonen, Elina (2015) LAPTM4B facilitates late endosomal ceramide export to control cell death pathways. .
- Frechin, Mathieu; Stoeger, Thomas; Daetwyler, Stephan; Gehin, Charlotte; Battich, Nico; Damm, Eva-Maria; Stergiou, Lilli; Riezman, Howard; Pelkmans, Lucas (2015) Cell-intrinsic adaptation of lipid composition to local crowding drives social behaviour. .
- Aimo, Lucila; Liechti, Robin; Nouspikel, Nevila; Niknejad, Anne; Gleizes, Anne; Gotz, Lou; Kuznetsov, Dmitry; David, Fabrice P. A.; van der Gout, Gisou; Riezman, Howard; Bougueleret, Lydie; Xenarios, Ioannis; Bridge, Alan (2015) The SwissLipids knowledgebase for lipid biology. .
- Suresh, Harsha Garadi; da Silveira dos Santos, Aline Xavier; Kukulski, Wanda; Tyedmers, Jens; Riezman, Howard; Bukau, Bernd; Mogk, Axel (2015) Prolonged starvation drives reversible sequestration of lipid biosynthetic enzymes and organelle reorganization in Saccharomyces cerevisiae. .
- Manzano-Lopez, Javier; Perez-Linero, Ana M.; Aguilera-Romero, Auxiliadora; Martin, Maria E.; Okano, Tatsuki; Silva, Daniel Varon; Seeberger, Peter H.; Riezman, Howard; Funato, Kouichi; Goder, Veit; Wellinger, Ralf E.; Muñiz, Manuel (2015) COPII Coat Composition Is Actively Regulated by Luminal Cargo Maturation. .
- Wilson-Zbinden, Caroline; dos Santos, Aline Xavier da Silveira; Stoffel-Studer, Ingrid; van der Vaart, Aniek; Hofmann, Kay; Reggiori, Fulvio; Riezman, Howard; Kraft, Claudine; Peter, Matthias (2015) Autophagy Competes for a Common Phosphatidylethanolamine Pool with Major Cellular PE-Consuming Pathways in Saccharomyces cerevisiae. .
2014
- Loizides-Mangold, Ursula; Clément, Sophie; Alfonso-Garcia, Alba; Branche, Emilie; Conzelmann, Stéphanie; Parisot, Clotilde; Potma, Eric O.; Riezman, Howard; Negro, Francesco; Jhaveri, Ravi (2014) HCV 3a Core Protein Increases Lipid Droplet Cholesteryl Ester Content via a Mechanism Dependent on Sphingolipid Biosynthesis. .
- da Silveira dos Santos, Aline Xavier; Riezman, Isabelle; Aguilera-Romero, Maria-Auxiliadora; David, Fabrice; Piccolis, Manuele; Loewith, Robbie; Schaad, Olivier; Riezman, Howard (2014) Systematic lipidomic analysis of yeast protein kinase and phosphatase mutants reveals novel insights into regulation of lipid homeostasis. .
- Lakshminarayanan, Rajamani; Liu, Shouping; Li, Jianguo; Nandhakumar, Muruganantham; Aung, Thet Tun; Goh, Eunice; Chang, Jamie Ya Ting; Saraswathi, Padhmanaban; Tang, Charles; Safie, Siti Radiah Binte; Lin, Lim Yih; Riezman, Howard; Lei, Zhou; Verma, Chandra S.; Beuerman, Roger W.; Khan, Rizwan H. (2014) Synthetic Multivalent Antifungal Peptides Effective against Fungi. .
- Prifti, Efthymia; Reymond, Luc; Umebayashi, Miwa; Hovius, Ruud; Riezman, Howard; Johnsson, Kai (2014) A Fluorogenic Probe for SNAP-Tagged Plasma Membrane Proteins Based on the Solvatochromic Molecule Nile Red. .
- Kajiwara, Kentaro; Ikeda, Atsuko; Aguilera-Romero, Auxiliadora; Castillon, Guillaume A.; Kagiwada, Satoshi; Hanada, Kentaro; Riezman, Howard; Muñiz, Manuel; Funato, Kouichi (2014) Osh proteins regulate COPII-mediated vesicular transport of ceramide from the endoplasmic reticulum in budding yeast. .
- Aguilera-Romero, Auxiliadora; Gehin, Charlotte; Riezman, Howard (2014) Sphingolipid homeostasis in the web of metabolic routes. .
2013
- Cohen, Yifat; Megyeri, Márton; Chen, Oscar C. W.; Condomitti, Giuseppe; Riezman, Isabelle; Loizides-Mangold, Ursula; Abdul-Sada, Alaa; Rimon, Nitzan; Riezman, Howard; Platt, Frances M.; Futerman, Anthony H.; Schuldiner, Maya; Michnick, Stephen W. (2013) The Yeast P5 Type ATPase, Spf1, Regulates Manganese Transport into the Endoplasmic Reticulum. .
- Zimmermann, Christine; Santos, Aline; Gable, Kenneth; Epstein, Sharon; Gururaj, Charulatha; Chymkowitch, Pierre; Pultz, Dennis; Rødkær, Steven V.; Clay, Lorena; Bjørås, Magnar; Barral, Yves; Chang, Amy; Færgeman, Nils J.; Dunn, Teresa M.; Riezman, Howard; Enserink, Jorrit M. (2013) TORC1 Inhibits GSK3-Mediated Elo2 Phosphorylation to Regulate Very Long Chain Fatty Acid Synthesis and Autophagy. .
- Ding, Jun; Loizides-Mangold, Ursula; Rando, Gianpaolo; Zoete, Vincent; Michielin, Olivier; Reddy, Janardan K.; Wahli, Walter; Riezman, Howard; Thorens, Bernard (2013) The Peroxisomal Enzyme L-PBE Is Required to Prevent the Dietary Toxicity of Medium-Chain Fatty Acids. .
- Lindberg, Lina; Santos, Aline XS.; Riezman, Howard; Olsson, Lisbeth; Bettiga, Maurizio; Oresic, Matej (2013) Lipidomic Profiling of Saccharomyces cerevisiae and Zygosaccharomyces bailii Reveals Critical Changes in Lipid Composition in Response to Acetic Acid Stress. .
- Gehin, Charlotte; Montenegro, Javier; Bang, Eun-Kyoung; Cajaraville, Ana; Takayama, Shota; Hirose, Hisaaki; Futaki, Shiroh; Matile, Stefan; Riezman, Howard (2013) Dynamic Amphiphile Libraries to Screen for the “Fragrant” Delivery of siRNA into HeLa Cells and Human Primary Fibroblasts. .
- Epstein, Sharon; Riezman, Howard (2013) Sphingolipid signaling in yeast: potential implications for understanding disease. .
2012
- Santos, Aline X. S.; Riezman, Howard (2012) Yeast as a model system for studying lipid homeostasis and function. .
- Jarmoszewicz, Katarzyna; Łukasiak, Katarzyna; Riezman, Howard; Kaminska, Joanna; Polymenis, Michael (2012) Rsp5 Ubiquitin Ligase Is Required for Protein Trafficking in Saccharomyces cerevisiae COPI Mutants. .
- Loizides-Mangold, Ursula; David, Fabrice P. A.; Nesatyy, Victor J.; Kinoshita, Taroh; Riezman, Howard (2012) Glycosylphosphatidylinositol anchors regulate glycosphingolipid levels. .
- Epstein, Sharon; Castillon, Guillaume A.; Qin, Yongmei; Riezman, Howard (2012) An essential function of sphingolipids in yeast cell division. .
- Berchtold, Doris; Piccolis, Manuele; Chiaruttini, Nicolas; Riezman, Isabelle; Riezman, Howard; Roux, Aurélien; Walther, Tobias C.; Loewith, Robbie (2012) Plasma membrane stress induces relocalization of Slm proteins and activation of TORC2 to promote sphingolipid synthesis. .
- Alonso Doval, David; Fin, Andrea; Takahashi-Umebayashi, Miwa; Riezman, Howard; Roux, Aurelien; Sakai, Naomi; Matile, Stefan (2012) Amphiphilic Dynamic NDI and PDI Probes: Imaging Microdomains in Giant Unilamellar Vesicles. .
- Epstein, Sharon; Kirkpatrick, Clare L.; Castillon, Guillaume A.; Muniz, Manuel; Riezman, Isabelle; David, Fabrice P. A.; Wollheim, Claes B.; Riezman, Howard (2012) Activation of the unfolded protein response pathway causes ceramide accumulation in yeast and INS-1E insulinoma cells. .
- Jennemann, Richard; Rabionet, Mariona; Gorgas, Karin; Epstein, Sharon; Dalpke, Alexander; Rothermel, Ulrike; Bayerle, Aline; van der Hoeven, Franciscus; Imgrund, Silke; Kirsch, Joachim; Nickel, Walter; Willecke, Klaus; Riezman, Howard; Grone, Hermann-Josef; Sandhoff, Roger (2012) Loss of ceramide synthase 3 causes lethal skin barrier disruption. .
2011
- Alvarez-Vasquez, Fernando; Riezman, Howard; Hannun, Yusuf A.; Voit, Eberhard O.; Zhang, Zhengguang (2011) Mathematical Modeling and Validation of the Ergosterol Pathway in Saccharomyces cerevisiae. .
- Takahashi-Umebayashi, Miwa; Pineau, Ludovic; Hannich, Thomas; Zumbuehl, Andreas; Alonso Doval, David; Matile, Stefan; Heinis, Christian; Turcatti, Gerardo; Loewith, Robbie; Roux, Aurelien; Reymond, Luc; Johnsson, Kai; Riezman, Howard (2011) Chemical Biology Approaches to Membrane Homeostasis and Function. .
- Montenegro, Javier; Gehin, Charlotte; Bang, Eun-Kyoung; Fin, Andrea; Alonso Doval, David; Riezman, Howard; Sakai, Naomi; Matile, Stefan (2011) Conceptually New Entries into Cells. .
- Sturzenegger, Susi; Johnsson, Kai; Riezman, Howard (2011) NCCR Chemical Biology: Interdisciplinary Research Excellence, Outreach, Education, and New Tools for Switzerland. .
- Lissina, Elena; Young, Brian; Urbanus, Malene L.; Guan, Xue Li; Lowenson, Jonathan; Hoon, Shawn; Baryshnikova, Anastasia; Riezman, Isabelle; Michaut, Magali; Riezman, Howard; Cowen, Leah E.; Wenk, Markus R.; Clarke, Steven G.; Giaever, Guri; Nislow, Corey; Cooper, Sara J. (2011) A Systems Biology Approach Reveals the Role of a Novel Methyltransferase in Response to Chemical Stress and Lipid Homeostasis. .
- Ternes, Philipp; Feussner, Kirstin; Werner, Stephanie; Lerche, Jennifer; Iven, Tim; Heilmann, Ingo; Riezman, Howard; Feussner, Ivo (2011) Disruption of the ceramide synthase LOH1 causes spontaneous cell death in Arabidopsis thaliana. .
- Fujita, Morihisa; Watanabe, Reika; Jaensch, Nina; Romanova-Michaelides, Maria; Satoh, Tadashi; Kato, Masaki; Riezman, Howard; Yamaguchi, Yoshiki; Maeda, Yusuke; Kinoshita, Taroh (2011) Sorting of GPI-anchored proteins into ER exit sites by p24 proteins is dependent on remodeled GPI. .
- Souza, Cleiton M.; Schwabe, Tatjana M.E.; Pichler, Harald; Ploier, Birgit; Leitner, Erich; Guan, Xue Li; Wenk, Markus R.; Riezman, Isabelle; Riezman, Howard (2011) A stable yeast strain efficiently producing cholesterol instead of ergosterol is functional for tryptophan uptake, but not weak organic acid resistance. .
- Castillon, Guillaume A.; Aguilera-Romero, Auxiliadora; Manzano-Lopez, Javier; Epstein, Sharon; Kajiwara, Kentaro; Funato, Kouichi; Watanabe, Reika; Riezman, Howard; Muniz, Manuel (2011) The yeast p24 complex regulates GPI-anchored protein transport and quality control by monitoring anchor remodeling. .
- Hannich, J. Thomas; Umebayashi, Kyohei; Riezman, Howard (2011) Distribution and Functions of Sterols and Sphingolipids. .
- Shivapurkar, Rupali; Souza, Cleiton M.; Jeannerat, Damien; Riezman, Howard (2011) An Efficient Method for the Production of Isotopically Enriched Cholesterol for NMR. .
- Ternes, Philipp; Wobbe, Tobias; Schwarz, Marnie; Albrecht, Sandra; Feussner, Kirstin; Riezman, Isabelle; Cregg, James M.; Heinz, Ernst; Riezman, Howard; Feussner, Ivo; Warnecke, Dirk (2011) Two Pathways of Sphingolipid Biosynthesis Are Separated in the Yeast Pichia pastoris. .
2010
- Carvalho, Maria; Schwudke, Dominik; Sampaio, Julio L.; Palm, Wilhelm; Riezman, Isabelle; Dey, Gautam; Gupta, Gagan D.; Mayor, Satyajit; Riezman, Howard; Shevchenko, Andrej; Kurzchalia, Teymuras V.; Eaton, Suzanne (2010) Survival strategies of a sterol auxotroph. .
- Bourquin, Florence; Riezman, Howard; Capitani, Guido; Grütter, Markus G. (2010) Structure and Function of Sphingosine-1-Phosphate Lyase, a Key Enzyme of Sphingolipid Metabolism. .
- Guan, Xue Li Riezman, Isabelle Wenk, Markus R. Riezman, Howard (2010) Yeast Lipid Analysis and Quantification by Mass Spectrometry. .
2009
- González-Gaitán, Marcos; Gruenberg, Jean; Halazonetis, Thanos; Laemmli, Ulrich K.; Matter, Jean-Marc; Riezman, Howard; Schaad, Olivier; Soldati, Thierry; Watanabe, Reika (2009) The Biochemistry Department of the AVƵ: Understanding the Molecular Basis and Function of Intracellular Organization. .
- Deshusses, Jacques; Riezman, Howard (2009) History of Biochemistry at the AVƵ: From the Boulevard des Philosophes to Quai Ernest-Ansermet. .
- Castillon, Guillaume A. Riezman, Howard (2009) Transport of GPI-Anchored Proteins: Connections to Sphingolipid and Sterol Transport. .
- Hannich, J. Thomas; Entchev, Eugeni V.; Mende, Fanny; Boytchev, Hristio; Martin, René; Zagoriy, Vyacheslav; Theumer, Gabriele; Riezman, Isabelle; Riezman, Howard; Knölker, Hans-Joachim; Kurzchalia, Teymuras V. (2009) Methylation of the Sterol Nucleus by STRM-1 Regulates Dauer Larva Formation in Caenorhabditis elegans. .
- Menuz, Vincent; Howell, Kate S.; Gentina, Sébastien; Epstein, Sharon; Riezman, Isabelle; Fornallaz-Mulhauser, Monique; Hengartner, Michael O.; Gomez, Marie; Riezman, Howard; Martinou, Jean-Claude (2009) Protection of C. elegans from Anoxia by HYL-2 Ceramide Synthase. .
- Guan, Xue Li; Souza, Cleiton M.; Pichler, Harald; Dewhurst, Gisèle; Schaad, Olivier; Kajiwara, Kentaro; Wakabayashi, Hirotomo; Ivanova, Tania; Castillon, Guillaume A.; Piccolis, Manuele; Abe, Fumiyoshi; Loewith, Robbie; Funato, Kouichi; Wenk, Markus R.; Riezman, Howard (2009) Functional Interactions between Sphingolipids and Sterols in Biological Membranes Regulating Cell Physiology. .
- Castillon, Guillaume A.; Watanabe, Reika; Taylor, Marcia; Schwabe, Tatjana M. E.; Riezman, Howard (2009) Concentration of GPI-Anchored Proteins upon ER Exit in Yeast. .
2008
- Watanabe, Reika; Castillon, Guillaume A.; Meury, Anja; Riezman, Howard (2008) The presence of an ER exit signal determines the protein sorting upon ER exit in yeast. .
- Mukhopadhyay, Debdyuti; Howell, Kate S.; Riezman, Howard; Capitani, Guido (2008) Identifying Key Residues of Sphinganine-1-phosphate Lyase for Function in Vivo and in Vitro. .
- Idrissi, Fatima-Zahra; Grötsch, Helga; Fernández-Golbano, Isabel M.; Presciatto-Baschong, Cristina; Riezman, Howard; Geli, María-Isabel (2008) Distinct acto/myosin-I structures associate with endocytic profiles at the plasma membrane. .
- Kajiwara, Kentaro; Watanabe, Reika; Pichler, Harald; Ihara, Kensuke; Murakami, Suguru; Riezman, Howard; Funato, Kouichi (2008) Yeast ARV1 Is Required for Efficient Delivery of an Early GPI Intermediate to the First Mannosyltransferase during GPI Assembly and Controls Lipid Flow from the Endoplasmic Reticulum. .
- Aguilera-Romero, Auxiliadora; Kaminska, Joanna; Spang, Anne; Riezman, Howard; Muñiz, Manuel (2008) The yeast p24 complex is required for the formation of COPI retrograde transport vesicles from the Golgi apparatus. .
- te Welscher, Yvonne M.; ten Napel, Hendrik H.; Balagué, Miriam Masià; Souza, Cleiton M.; Riezman, Howard; de Kruijff, Ben; Breukink, Eefjan (2008) Natamycin Blocks Fungal Growth by Binding Specifically to Ergosterol without Permeabilizing the Membrane. .
2007
- Riezman, Howard (2007) The Long and Short of Fatty Acid Synthesis. .
- Urban, Jörg; Soulard, Alexandre; Huber, Alexandre; Lippman, Soyeon; Mukhopadhyay, Debdyuti; Deloche, Olivier; Wanke, Valeria; Anrather, Dorothea; Ammerer, Gustav; Riezman, Howard; Broach, James R.; De Virgilio, Claudio; Hall, Michael N.; Loewith, Robbie (2007) Sch9 Is a Major Target of TORC1 in Saccharomyces cerevisiae. .
- Mukhopadhyay, Debdyuti; Riezman, Howard (2007) Proteasome-Independent Functions of Ubiquitin in Endocytosis and Signaling. .
2006
- Kageyama-Yahara, Natsuko; Riezman, Howard (2006) Transmembrane topology of ceramide synthase in yeast. .
- Riezman, Howard (2006) Organization and functions of sphingolipid biosynthesis in yeast. .
- Grosshans, Bianka L.; Grötsch, Helga; Mukhopadhyay, Debdyuti; Fernandez, Isabel M.; Pfannstiel, Jens; Idrissi, Fatima-Zahra; Lechner, Johannes; Riezman, Howard; Geli, M. Isabel (2006) TEDS Site Phosphorylation of the Yeast Myosins I Is Required for Ligand-induced but Not for Constitutive Endocytosis of the G Protein-coupled Receptor Ste2p. .
- Meier, Karsten D.; Deloche, Olivier; Kajiwara, Kentaro; Funato, Kouichi; Riezman, Howard (2006) Sphingoid Base Is Required for Translation Initiation during Heat Stress in Saccharomyces cerevisiae. .
2004
- Pichler, Harald; Riezman, Howard (2004) Where sterols are required for endocytosis. .
- Watanabe, Reika; Riezman, Howard (2004) Differential ER exit in yeast and mammalian cells. .
2003
- Schaerer-Brodbeck, Claudia; Riezman, Howard (2003) Genetic and biochemical interactions between the Arp2/3 complex, Cmd1p, casein kinase II, and Tub4p in yeast. .
- Pomorski, Thomas; Lombardi, Ruben; Riezman, Howard; Devaux, Philippe F.; van Meer, Gerrit; Holthuis, Joost C. M.; Bonifacino, Juan (2003) Drs2p-related P-type ATPases Dnf1p and Dnf2p Are Required for Phospholipid Translocation across the Yeast Plasma Membrane and Serve a Role in Endocytosis. .
- Funato, Kouichi; Lombardi, Ruben; Vallée, Béatrice; Riezman, Howard (2003) Lcb4p Is a Key Regulator of Ceramide Synthesis from Exogenous Long Chain Sphingoid Base in Saccharomyces cerevisiae. .
2002
- Funato, Kouichi; Vallée, Béatrice; Riezman, Howard (2002) Biosynthesis and Trafficking of Sphingolipids in the Yeast. .
2001
- Muñiz, Manuel; Morsomme, Pierre; Riezman, Howard (2001) Protein Sorting upon Exit from the Endoplasmic Reticulum. .
2000
- Schaerer-Brodbeck, Claudia; Riezman, Howard (2000) Interdependence of Filamentous Actin and Microtubules for Asymmetric Cell Division. .
1996
- Riezman, Howard; Munn, A.; Geli, M. I.; Hicke, L. (1996) Actin-, myosin- and ubiquitin-dependent endocytosis. .